: Resveratrol May Promote New Blood Vessel Growth After a Stroke
By a News Reporter-Staff News Editor at Angiogenesis Weekly
According to news reporting from Charlestown, Massachusetts, by NewsRx journalists, research stated, "Resveratrol may be a powerful way of protecting the brain against a wide variety of stress and injury. Recently, it has been proposed that resveratrol not only reduces brain injury but also promotes recovery after stroke."
The news correspondents obtained a quote from the research from the Harvard School of Medicine, "But the underlying mechanisms are unclear. Here, we tested the hypothesis that resveratrol promotes angiogenesis( new blood vessel growth) in cerebral endothelial cells and dissected the signaling pathways involved. Treatment of cerebral endothelial cells with resveratrol promoted proliferation, migration, and tube formation. According to the news reporters, the research concluded: "These findings provide a mechanistic basis for the potential use of resveratrol as a candidate therapy to promote angiogenesis and neurovascular recovery after stroke."
For more information on this research see: Pro-angiogenic effects of resveratrol in brain endothelial cells: nitric oxide-mediated regulation of vascular endothelial growth factor and metalloproteinases. Journal of Cerebral Blood Flow and Metabolism, 2012;32(5):884-95. (Nature Publishing Group - www.nature.com/; Journal of Cerebral Blood Flow and Metabolism - www.nature.com/jcbfm/)
Our news journalists report that additional information may be obtained by contacting F. Simao, Departments of Radiology and Neurology, Neuroprotection Research Laboratory, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, United States (see also Angiogenesis).
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