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Minocycline Hydrochloride Periodontal Microspheres


Related terms
Author information


    Related terms
    • Brand Names: U.S.: Arestin®

    • It is used to treat swelling of the tissue around the teeth (periodontitis). It is used with scaling and root planing.
    • Minocycline works to harm the bacteria and fight the infection.


    How to take

    • This drug will be given to you by a doctor.

    Missed Dose

    • Call your doctor for an office visit.


    • This drug will be given to you in a hospital or doctor's office. You will not store it at home.



    • If you have an allergy to minocycline or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you are pregnant or may be pregnant.


    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Do not chew hard, crusty, or sticky foods.
    • Do not brush or floss near the area for 12 hours.
    • You may get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen and wear clothing and eyewear that protects you from the sun.
    • Use birth control that you can trust to stop pregnancy while taking this drug.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • Pain where it was placed.
    • Mouth irritation or sores. Using a soft toothbrush or cotton swabs and rinsing the mouth may help. Do not use mouth rinses that have alcohol in them.
    • Headache.


    • Change in the health problem being treated. Is it better, worse, or about the same?
    • Follow up with the doctor.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Very bad pain, swelling, or bleeding where treated.
    • Very loose stools (diarrhea), even after drug is stopped.
    • Very bad headache.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (

    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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