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    Related terms
    • Brand Names: U.S.: Trandate®
    • Brand Names: Canada: Apo-Labetalol®;Labetalol Hydrochloride Injection, USP;Normodyne®;Trandate®

    • It is used to treat high blood pressure.
    • Labetalol blocks chemicals that fire up the body.


    How to take

    • Oral:
    • Take as you have been told, even if you are feeling better.
    • Take this drug with food.
    • Follow the diet and workout plan that your doctor told you about.
    • Shot:
    • It is given as a shot into a vein.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.
    • Do not change the dose or stop this drug. Talk with the doctor.


    • Store at room temperature.
    • Protect tablets from water. Do not store in a bathroom or kitchen.
    • The shot will be given to you in a hospital or doctor's office. You will not store it at home.



    • Do not stop taking this drug all of a sudden. To avoid side effects, you will want to slowly stop it.
    • Sometimes drugs are not safe when you take them with certain other drugs. Taking them together can cause bad side effects. This is one of those drugs. Be sure to talk to your doctor about all the drugs you take.


    • If you have an allergy to labetalol or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have any of these health problems: Asthma, poor electrical activity in the heart without a working pacemaker, very weak heart, or slow heartbeat.
    • If you are more than 12 weeks pregnant.


    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Do not run out of this drug.
    • Wear disease medical alert ID (identification).
    • If you have high blood sugar (diabetes) and have low blood sugar, talk with your doctor. This drug hides the signs of low blood sugar except sweating.
    • If you have liver disease, talk with your doctor.
    • If you have lung disease, talk with your doctor.
    • If you have mental illness, talk with your doctor.
    • If you have myasthenia gravis, talk with your doctor.
    • If you have a weak heart, talk with your doctor.
    • Have your blood pressure and heart rate checked often. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • If you are taking this drug and have high blood pressure, talk with your doctor before using OTC products that may raise blood pressure. These include cough or cold drugs, diet pills, stimulants, ibuprofen or like products, and some natural products or aids.
    • Use birth control that you can trust to stop pregnancy while taking this drug.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Feeling tired or weak.
    • Change in sex ability. This most often goes back to normal.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Very bad dizziness or passing out.
    • Very upset stomach or throwing up.
    • Trouble breathing.
    • A big weight gain.
    • Feeling very tired or weak.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

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    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (

    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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