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    Related terms
    • Brand Names: U.S.: Crixivan®
    • Brand Names: Canada: Crixivan®

    • It is used to treat HIV infection.
    • Indinavir works to harm the virus and fight the infection.


    How to take

    • Use as you have been told, even if you are feeling better.
    • Take with water, juice, skim milk, coffee, tea, or a light snack. Take 1 hour before or 2 hours after meals.
    • If taking this drug with ritonavir, take with food.
    • Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.

    Missed Dose

    • Take a missed dose as soon as you think about it and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.
    • Do not change the dose or stop this drug. Talk with the doctor.


    • Store in the original container. Do not take out the antimoisture cube.
    • Protect from water. Do not store in a bathroom or kitchen.



    • This drug may raise the chance of kidney stones. Be sure to drink lots of fluids while taking this drug. Children are more likely to get kidney stones than adults.
    • Sometimes drugs are not safe when you take them with certain other drugs. Taking them together can cause bad side effects. This is one of those drugs. Be sure to talk to your doctor about all the drugs you take.


    • If you have an allergy to indinavir or any other part of this drug.


    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Do not run out of this drug.
    • If you have hemophilia, talk with your doctor.
    • If you have high blood sugar (diabetes), this drug may sometimes raise blood sugar. Talk with your doctor about how to fine tune this.
    • If you have kidney disease, talk with your doctor.
    • If you have liver disease, talk with your doctor.
    • Have your blood work checked often. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Do not take didanosine within 1 hour of this drug.
    • To protect from diseases caused by having sex, use a latex condom.
    • Use birth control that you can trust to stop pregnancy in HIV disease.
    • Do not use a hormone-related kind of birth control.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Do not breast-feed if you have HIV disease and live in the U.S.

    Side Effects

    • High cholesterol level. Check level before starting this drug.
    • High triglyceride level. Check level before starting this drug.
    • Headache.
    • Belly pain.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Loose stools (diarrhea).
    • Change in body fat.
    • Feeling tired or weak.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Back pain, blood in the urine, or fever or chills.
    • Very upset stomach or throwing up.
    • Very loose stools (diarrhea).
    • More trips to the bathroom, more thirst, or weight loss.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

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    Copyright © 2011 Natural Standard (

    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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