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Fluticasone and Salmeterol

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Advair Diskus®;Advair® HFA
    • Brand Names: Canada: Advair Diskus®;Advair®
    • Mexican Brand Names: Seretide
    • Pharmacologic Category: Beta2-Adrenergic Agonist;Beta2-Adrenergic Agonist, Long-Acting;Corticosteroid, Inhalant (Oral)

    Uses
    • It is used to open the airways in lung diseases where spasm may cause breathing problems.
    • It is used to treat asthma.
    • It may take 1 week to see the full effect.
    • Fluticasone stops or lowers irritation and swelling.
    • Salmeterol works in the airways to calm the muscles and help the flow of oxygen.

    Dosing

    How to take

    • For breathing in only.
    • Shake Advair® HFA well before use.
    • Prepare puffer (inhaler) before first use or when puffer has not been used for more than 4 weeks. Spray 4 test sprays into the air.
    • If you are using more than 1 type of puffer (inhaler), ask your doctor which puffer to use first.
    • Rinse out mouth after each use.
    • Have your puffer (inhaler) use checked with your doctor at each visit. Read and follow facts on how to use the puffer. Make sure you use the puffer the right way.

    Missed Dose

    • Use a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not use 2 doses or extra doses.
    • Do not change the dose or stop this drug. Talk with the doctor.

    Storage

    • Store at room temperature.
    • Advair® Diskus®: Throw away any part not used after 1 month or when the indicator reads zero, whichever comes first.
    • Advair® HFA: Throw away when the indicator reads zero.
    • Protect from heat.
    • Protect from light.
    • Protect from water. Do not store in a bathroom or kitchen.

    Safety



    Warnings

    • When changing from an oral steroid to a breathed in one, there may be problems. Signs such as weakness, feeling tired, dizziness, upset stomach, throwing up, not thinking clearly, or low blood sugar may happen. Call your doctor right away if you have any of these signs. If you have a bad crash and are harmed, have surgery, or any type of infection, you may need extra doses of oral steroids. These extra steroids will help your body deal with these stresses. Carry a warning card saying that there may be times when you may need extra steroids.
    • In patients with asthma, long-acting puffers (inhalers) raised asthma-related deaths. Talk with the doctor.
    • Unsafe side effects may happen. This drug cannot be taken while you are taking some other drugs. Check all the drugs you are taking with your doctor.
    • Please read the medication guide.

    Avoid

    • If you have an allergy to fluticasone, salmeterol, or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you are having a breathing attack.
    • If you are allergic to milk, talk with the doctor.

    Precautions

    • Wear disease medical alert ID (identification).
    • Do not use this drug to treat an asthma attack. Use a short-acting puffer (inhaler).
    • If you have high blood sugar (diabetes), talk with your doctor.
    • If you have a fast heartbeat, talk with your doctor.
    • If you have heart disease, talk with your doctor.
    • If you have high blood pressure, talk with your doctor.
    • If you have liver disease, talk with your doctor.
    • If you have soft, brittle bones (osteoporosis), talk with your doctor.
    • If you have an overactive thyroid, talk with your doctor.
    • If you have seizures, talk with your doctor.
    • If you are being treated for any infection, talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Limit your use of caffeine (for example, tea, coffee, cola) and chocolate. Use with this drug may cause nervousness, shakiness, and a fast heartbeat.
    • Avoid grapefruit and grapefruit juice.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • Headache.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Cough.
    • Throat irritation.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain.
    • Feeling very tired, weak, or touchy; trembling; having a fast heartbeat, confusion, sweating, or dizziness if you missed a dose or recently stopped this drug.
    • If you are not able to get the breathing attack under control. Get help right away.
    • Chest pain or pressure or a fast heartbeat.
    • Peak flow measurement low.
    • Use of short-acting puffer (inhaler) more often.
    • Very nervous and excitable.
    • If you have been exposed to chickenpox or measles and have not had chickenpox or measles or had a chickenpox or measles vaccine.
    • Any rash.
    • Health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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