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Related terms
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    Related terms
    • Brand Names: U.S.: Apokyn®

    • It is used to treat Parkinson's disease.
    • Apomorphine is used to treat a chemical imbalance in Parkinson's disease.


    How to take

    • It is given as a shot into the fatty part of the skin.
    • Your doctor may teach you how to give the shot.
    • Wash your hands before and after use.
    • Throw syringe away after use. Do not use more than one time.
    • Throw away needles in a needle/sharp disposal box and take the box back to your doctor when it is full.

    Missed Dose

    • This drug is taken on an as needed basis.
    • If drug is stopped for more than 1 week, dose will need to be lowered.


    • Store at room temperature.



    • Sometimes drugs are not safe when you take them with certain other drugs. Taking them together can cause bad side effects. This is one of those drugs. Be sure to talk to your doctor about all the drugs you take.


    • If you have an allergy to apomorphine or any other part of this drug.
    • If you have a sulfite allergy, talk with your doctor.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.


    • If you have heart disease, talk with your doctor.
    • If you have low potassium levels or if you are taking a water pill, talk with your doctor.
    • If you have low magnesium levels, talk with your doctor.
    • If you have mental illness, talk with your doctor.
    • If you have had a stroke, talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Avoid beer, wine, mixed drinks, or other drugs and natural products that slow your actions.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you.
    • Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. You may need drugs to lower this side effect. Talk with your doctor.
    • Runny nose.
    • Yawning.


    • Change in the health problem being treated. Is it better, worse, or about the same?
    • Follow up with the doctor.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Very bad dizziness or passing out.
    • Change in thinking clearly and with logic.
    • Falling asleep during activities such as eating or talking.
    • Big change in balance.
    • Very upset stomach or throwing up.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (

    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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