Table of Contents > Drug > Efavirenz, Emtricitabine, and Tenofovir Print

Efavirenz, Emtricitabine, and Tenofovir

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Atripla®
    • Brand Names: Canada: Atripla®
    • Pharmacologic Category: Antiretroviral Agent, Reverse Transcriptase Inhibitor (Non-nucleoside);Antiretroviral Agent, Reverse Transcriptase Inhibitor (Nucleoside);Antiretroviral Agent, Reverse Transcriptase Inhibitor (Nucleotide)

    Uses
    • It is used to treat HIV infection.
    • Efavirenz, emtricitabine, and tenofovir works to harm the virus and fight the infection.

    Dosing

    How to take

    • To gain the most benefit, do not miss doses.
    • Use as you have been told, even if you are feeling better.
    • Take on an empty stomach. Take 1 hour before or 2 hours after meals.
    • Take at bedtime if it causes sleepiness.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.
    • Do not change the dose or stop this drug. Talk with the doctor.

    Storage

    • Store at room temperature.
    • Protect from water. Do not store in a bathroom or kitchen.

    Safety



    Warnings

    • This drug may cause liver problems and a change in acid levels in the blood. Closely read the part in this leaflet which lists when to call your doctor. Pregnancy, obesity, and/or longer therapy may raise this chance.
    • Hepatitis B testing may be done in patients taking this drug for HIV infection. A hepatitis B infection may get worse after this drug is stopped.
    • Unsafe side effects may happen. This drug cannot be taken while you are taking some other drugs. Check all the drugs you are taking with your doctor.

    Avoid

    • If you have an allergy to efavirenz, emtricitabine, tenofovir, or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you are pregnant or may be pregnant.

    Precautions

    • Do not run out of this drug.
    • If you have kidney disease, talk with your doctor.
    • If you have liver disease, talk with your doctor.
    • Have your blood work checked often. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • You may not be alert. Avoid driving and doing other tasks or actions until you see how this drug affects you.
    • Avoid beer, wine, mixed drinks, or other drugs and natural products that slow your actions.
    • To protect from diseases caused by having sex, use a latex condom.
    • Use birth control that you can trust to stop pregnancy in HIV disease.
    • Birth control pills and other hormone-based birth control may not work to stop pregnancy. Use some other kind of birth control while taking this drug.
    • Do not breast-feed if you have HIV disease and live in the U.S.

    Side Effects

    • Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you.
    • Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing.
    • Headache.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Loose stools.
    • Weak bones.
    • Change in color of skin.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Trouble breathing.
    • Very bad dizziness.
    • Feeling cold.
    • Signs of low mood (depression), thoughts of killing yourself, nervousness, emotional ups and downs, thinking that is not normal, anxiety, or lack of interest in life.
    • Feeling very tired or weak.
    • Dark urine or yellow skin or eyes.
    • Very bad belly pain.
    • Very upset stomach or throwing up.
    • Not able to eat.
    • Very loose stools.
    • Very bad muscle pain or weakness.
    • Any rash.
    • Health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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