- MagnesiumMagnesium: According to human and animal studies, electrolyte disturbances, including low magnesium levels, may develop in a large proportion of patients receiving amphotericin B (12134234, 9177994, 2182052). According to human and animal studies, lipid-based formulations such as Abelcet® and Anphotec® may have a lesser effect than conventional formulations (2182052). This disturbance has been associated with nephrotoxicity and may necessitate discontinuing the drug and administering intravenous electrolyte replacement.
- PotassiumPotassium: According to animal study, amphotericin B (AMP-B) may induce potassium excretion defects (7948785). Hypokalaemia may be associated with acute myeloid leukemia after fluconazole treatment in humans (2565490).
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