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Bishop's weed (Ammi majus)



Interactions

Bishop's weed/Drug Interactions:
  • Anticoagulants and antiplateletsAnticoagulants and antiplatelets: According to a review, photoreactive furocoumarins (psoralens) have been identified in bishop's weed (2).
  • Cytochrome P450 metabolized agentsCytochrome P450 metabolized agents: Theoretically, bishop's weed may increase the effects of drugs metabolized by cytochrome P450. The bergapten constituent of bishop's weed is the same constituent as in grapefruit and bitter orange, which inhibits cytochrome P450.
  • Photosensitizing agentsPhotosensitizing agents: According to a review and case reports, bishop's weed may be photoreactive and phototoxic, potentially causing photosensitivity (10), phototoxic skin damage (2), contact urticaria (7), phototoxic dermatitis (7; 4), and pigmentary retinopathy (8).

Bishop's weed/Herb/Supplement Interactions:
  • Anticoagulants and antiplateletsAnticoagulants and antiplatelets: According to a review, photoreactive furocoumarins (psoralens) have been identified in bishop's weed (2).
  • Cytochrome P450 metabolized herbs and supplementsCytochrome P450 metabolized herbs and supplements: Theoretically, bishop's weed may increase the effects of herbs/supplements metabolized by cytochrome P450. The bergapten constituent of bishop's weed is the same constituent as in grapefruit and bitter orange, which inhibits cytochrome P450.
  • PhotosensitizersPhotosensitizers: According to a review and case reports, bishop's weed may be photoreactive and phototoxic, potentially causing photosensitivity (10), phototoxic skin damage (2), contact urticaria (7), phototoxic dermatitis (7; 4), and pigmentary retinopathy (8).

Bishop's weed/Food Interactions:
  • Insufficient available evidence.

Bishop's weed/Lab Interactions:
  • Coagulation panelCoagulation panel: According to a review, photoreactive furocoumarins (psoralens) have been identified in bishop's weed (2).

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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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